Pathology EMQ template.

Name: Adam Clare

Candidate number:

Theme: Coagulation

OPTION LIST

A	Antithrombin	I	Factor Xa
B	Factor II	J	Plasmin
C	Factor III	K	Protein C
D	Factor V	L	Protein S
E	Factor VII	M	Thrombin
F	Factor VIII	N	vWF
G	Factor IX	O
H	Factor X	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. A 12 year old boy presents to A+E with a laceration on his forehead that won’t seem to stop bleeding. Investigations reveal a prolonged APTT, but normal PT and bleeding time. Which clotting factor is this patient most likely to be deficient in?

2. Which clotting factor binds to exposed tissue factor following endothelial injury?

3. Inactivates factors V and VIII.

4. A 19 year old woman visits her GP concerned because she noticed prolonged bleeding from her gums following some dental treatment. She also admits to suffering from frequent nose bleeds. Investigation reveals a prolonged APTT and bleeding time but normal PT. What is she likely to be deficient in?

5. This clotting factor, in complex with factor Va converts prothrombin to thrombin.

ANSWERS

1. F

2. E

3. K

4. N

5. I